Key result
Korean patients with acute myocardial infarction exhibit different risk factors, higher STEMI incidence, and distinct responses to medical and interventional treatments compared to Western populations.
The KAMIR registry highlights unique clinical characteristics, risk factors, and treatment responses in Korean AMI patients compared to Western populations, emphasizing the need for Asia-specific guidelines.
May warrant ethnicity-specific AMI risk assessment; leaves open Asia-specific guideline development pending prospective validation.
The Korea Acute Myocardial Infarction Registry (KAMIR) is the first nationwide registry that reflects current therapeutic approaches and acute myocardial infarction (AMI) management in Korea. The results of the KAMIR demonstrated different risk factors and responses to medical and interventional treatments. The results indicated that the incidence of ST-elevation myocardial infarction (STEMI) was relatively high, and that the prevalence of dyslipidemia was relatively low with higher triglyceride and lower high-density lipoprotein cholesterol levels. Percutaneous coronary intervention (PCI) rates were high for both STEMI and non-ST-elevation myocardial infarction (NSTEMI) with higher use of drug-eluting stents (DESs). DES were effective and safe without increased risk of stent thrombosis in Korean AMI patients. Triple antiplatelet therapy, consisting of aspirin, clopidogrel, and cilostazol, was effective in preventing adverse clinical outcomes after PCI. Statin therapy was effective in Korean AMI patients, including those with very low levels of low-density lipoprotein cholesterol and those with cardiogenic shock. The KAMIR score had a greater predictive value than Thrombolysis in Myocardial Infarction (TIMI) and Global Registry of Acute Coronary Events (GRACE) scores for long-term mortality in AMI patients. Based on these results, the KAMIR will be instrumental for establishing new therapeutic strategies and effective methods for secondary prevention of AMI and guidelines for Asian patients.
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Doo Sun Sim (2017) conducted a review in Acute myocardial infarction (n=62,000). Korean Acute Myocardial Infarction Registry (KAMIR) patient characteristics vs. Western AMI registries was evaluated. Korean patients with acute myocardial infarction exhibit different risk factors, higher STEMI incidence, and distinct responses to medical and interventional treatments compared to Western populations.
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