Key result
A higher triglyceride-glucose index was significantly associated with an increased prevalence of carotid atherosclerosis (OR 1.48) in middle-aged and elderly Chinese adults.
Why the study?
Evidence linking the triglyceride-glucose index to carotid atherosclerosis was limited and inconsistent due to small sample sizes or differences in study populations.
Is a higher triglyceride-glucose index associated with an increased prevalence of carotid atherosclerosis in middle-aged and elderly adults?
Cross-Sectional (n=59,123)
Yes
Is a higher triglyceride-glucose index associated with an increased prevalence of carotid atherosclerosis in middle-aged and elderly adults?
Odds Ratio: 1.48 (95% CI 1.39–1.56)
The triglyceride-glucose index is positively associated with carotid atherosclerosis, suggesting its potential utility as a simple surrogate marker for subclinical atherosclerosis risk assessment.
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Supports TyG index as potential surrogate marker; hypothesis-generating and requires prospective validation before clinical use.
Li et al. (2022) conducted a cross-sectional in Carotid atherosclerosis (n=59,123). Triglyceride-glucose (TyG) index vs. Lower TyG index was evaluated on Prevalence of carotid atherosclerosis (CA) (OR 1.48, 95% CI 1.39-1.56). A higher triglyceride-glucose index was significantly associated with an increased prevalence of carotid atherosclerosis (OR 1.48) in middle-aged and elderly Chinese adults.
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