What question did this study set out to answer?

To examine the relationship between outpatient sales of beta-lactam antibiotics and macrolides and penicillin nonsusceptibility in invasive Streptococcus pneumoniae isolates across Europe.

March 1, 2002Emerging infectious diseasesOpen Access

The Relationship between Antimicrobial Use and Antimicrobial Resistance in Europe

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Authors

SBS L A M BronzwaerEuropean Food Safety Authority OCOtto CarsUppsala University UBUdo BuchholzRobert Koch Institute

Discussion

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Implication

Surveillance study reveals a correlation between outpatient antibiotic sales and penicillin resistance in Streptococcus pneumoniae, highlighting how antimicrobial overuse drives resistance.

Key Points

To examine the relationship between outpatient sales of beta-lactam antibiotics and macrolides and penicillin nonsusceptibility in invasive Streptococcus pneumoniae isolates across Europe.
Gathered 1998–1999 surveillance data on penicillin resistance in invasive isolates of Streptococcus pneumoniae from the European Antimicrobial Resistance Surveillance System (EARSS).
Collected 1997 national outpatient sales figures for beta-lactam antibiotics and macrolides across participating European countries.
Penicillin nonsusceptibility in invasive Streptococcus pneumoniae isolates positively correlated with outpatient sales of beta-lactam antibiotics across European nations.
Resistance of Streptococcus pneumoniae to penicillin also exhibited a positive correlation with outpatient macrolide use.

Cite This Study

Bronzwaer et al. (2002) studied this question.

synapsesocial.com/papers/6a82fb895123f2a1809c8442 https://doi.org/10.3201/eid0803.010192

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March 1, 2002Emerging infectious diseasesOpen Access

The Relationship between Antimicrobial Use and Antimicrobial Resistance in Europe

View Full Paper

Ask AI

Bookmark

Authors

SBS L A M BronzwaerEuropean Food Safety Authority OCOtto CarsUppsala University UBUdo BuchholzRobert Koch Institute

Discussion

Member takes

Implication

Surveillance study reveals a correlation between outpatient antibiotic sales and penicillin resistance in Streptococcus pneumoniae, highlighting how antimicrobial overuse drives resistance.

Key Points

To examine the relationship between outpatient sales of beta-lactam antibiotics and macrolides and penicillin nonsusceptibility in invasive Streptococcus pneumoniae isolates across Europe.
Gathered 1998–1999 surveillance data on penicillin resistance in invasive isolates of Streptococcus pneumoniae from the European Antimicrobial Resistance Surveillance System (EARSS).
Collected 1997 national outpatient sales figures for beta-lactam antibiotics and macrolides across participating European countries.
Penicillin nonsusceptibility in invasive Streptococcus pneumoniae isolates positively correlated with outpatient sales of beta-lactam antibiotics across European nations.
Resistance of Streptococcus pneumoniae to penicillin also exhibited a positive correlation with outpatient macrolide use.

Cite This Study

Bronzwaer et al. (2002) studied this question.

synapsesocial.com/papers/6a82fb895123f2a1809c8442 https://doi.org/10.3201/eid0803.010192

Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

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