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Summary Serum levels of oestradiol‐l7β dehydrogenase have been determined in 113 normal pregnant women. The mean level increases ten‐fold from the 8th to the 40th week. Serum levels of this enzyme have been determined in women with threatened abortion in the first trimester and in women with intrauterine death of the fetus. Low or declining levels of the enzyme activity were associated with abortion, but the serum levels in cases of intrauterine fetal death corresponded to those of normal pregnancy.
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Plotti et al. (1972) studied this question.
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