Key result
Older healthy subjects exhibited morphological differences in their impedance cardiography waveforms compared to younger subjects, including an earlier initial upward deflection and an additional hump.
Why the study?
Knowledge on the morphology of the impedance cardiography signal is scarce compared with electrocardiography, particularly regarding age-dependent changes in waveforms.
Does age affect the morphology of the impedance cardiography signal in healthy volunteers?
Cross-Sectional (n=20)
No
Does age affect the morphology of the impedance cardiography signal in healthy volunteers?
Age-related changes in cardiovascular physiology, such as arterial stiffness, may manifest as distinct morphological differences in the impedance cardiography signal.
Answers are grounded in this paper and cite their sources.
Age-related impedance cardiography waveform changes may reflect vascular stiffening; leaves open need for age-specific norms before clinical adoption.
Impedance cardiography (ICG) is a non-invasive method of hemodynamic measurement, mostly known for estimation of stroke volume and cardiac output based on characteristic features of the signal. Compared with electrocardiography, the knowledge on the morphology of the ICG signal is scarce, especially with respect to age-dependent changes in ICG waveforms. Based on recordings from ten younger (20-29 years) and ten older (60-79) healthy human subjects after three different levels of physical activity, the typical interbeat ICG waveforms were derived based on ensemble averages. Comparison of these waveforms between the age groups indicates the following differences: a later initial upward deflection for the younger group, an additional hump in the waveform from many older subjects not presented in the younger group, and a more pronounced second wave in the younger group. The explanation for these differences is not clear, but may be related to arterial stiffness. Further studies are suggested to determine whether these morphological differences have clinical value.
No takes yet. Share an insight, caveat, or question.
Tronstad et al. (2019) conducted a cross-sectional in Healthy (n=20). Older age (60-79 years) vs. Younger age (20-29 years) was evaluated on Morphology of the impedance cardiography (ICG) signal. Older healthy subjects exhibited morphological differences in their impedance cardiography waveforms compared to younger subjects, including an earlier initial upward deflection and an additional hump.
Synapse has enriched 10 related papers. Consider them for comparative context: