Population
Theoretical models of vascular networks of increasing complexity, ranging from single-vessel resistance to…
Design
Preclinical
Authors
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Shear stress alone insufficient for stable networks in models; challenges prior assumptions and leaves open additional regulators.
Mathematical modeling reveals that local vessel wall shear stress alone is insufficient to control the growth and stability of complex vascular networks, indicating the necessity of additional regulatory factors.
Hacking et al. (1996) studied this question.
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