Key result
Postoperative statin therapy was associated with a significant reduction in total mortality (HR 0.48; 95% CI 0.28-0.82; P=0.007) and cardiovascular mortality after a first-ever CABG.
Why the study?
Does postoperative statin therapy reduce total and cardiovascular mortality in patients who survived a first-ever CABG surgery?
Observational (n=1,869)
Does postoperative statin therapy reduce total and cardiovascular mortality in patients who survived a first-ever CABG surgery?
Hazard Ratio: 0.48 (95% CI 0.28–0.82)
p-value: p=0.007
Postoperative statin therapy is associated with a 50% reduction in long-term total and cardiovascular mortality following a first-ever CABG.
No takes yet. Share an insight, caveat, or question.
May support postoperative statins after CABG; hypothesis-generating and leaves randomized confirmation open.
Παπαθανασίου et al. (2008) conducted an observational in first-ever coronary artery bypass grafting (CABG) surgery (n=1,869). statin therapy vs. no statin therapy was evaluated on Total mortality (HR 0.48, 95% CI 0.28-0.82, p=0.007). Postoperative statin therapy was associated with a significant reduction in total mortality (HR 0.48; 95% CI 0.28-0.82; P=0.007) and cardiovascular mortality after a first-ever CABG.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: