Publisher Summary This chapter focuses on the literature appearing during 1963–66 in the context of toxoplasmosis. The chapter outlines the advances in the electron microscopy of Toxoplasma and discusses the mechanisms of transmission, summarizing the serological work carried out in this regard. It also summarizes and comments on new epidemiological data and presents observations on the association of Toxoplasma with various disease conditions, papers concerned with anti-Toxoplasma drugs, and a few papers on physiology, tissue culture and toxin production of Toxoplasma. The usefulness of pyrimethamine and sulfa drugs in the treatment of toxoplasmosis has been generally accepted and well demonstrated. One disadvantage of pyrimethamine is teratogenesis. In addition, hematological side effects are frequently seen and must be monitored.
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Leon Jacobs (1963) studied this question.
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