The ability to suppress antibody response to specific antigens has been found to be inherent in a subpopulation of T lymphocytes. The suppressor pathway has been shown to involve an initial T-cell clone that that elaborates a soluble factor which, in turn, induces a second cohort of effector cells. The implications of this system for autoimmune and neoplastic diseases--and some relevant experiments--are discussed.
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Baruj Benacerraf (1978) studied this question.
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