Key result
RNA virome composition in pigs depended on animal age, differing between piglets and older pigs, but showed no clear differences between healthy and diarrheic pigs.
Why the study?
RNA viruses are considered important agents responsible for diarrhoea in pigs, motivating an analysis focused on the porcine enteric RNA virome.
Observational
The porcine enteric RNA virome composition depends primarily on the age of the pigs rather than the presence of diarrhea.
Should not guide diarrhea management in pigs; leaves open age-stratified viral roles for prospective study.
The porcine enteric virome comprises a wide range of eukaryotic and prokaryotic viruses in healthy and diarrheic pigs. As RNA viruses are considered to be important agents responsible for diarrhoea in pigs, this work was focused on the RNA virome. To identify viruses, a next generation sequencing technique and bioinformatics analysis was employed. A wide spectrum of viral genera with RNA genomes, such as Kobuvirus, Picobirnavirus, Teschovirus, Posavirus, Mamastovirus, Enterovirus and Rotavirus were identified in both diarrheic and healthy pigs. No clear differences in the virome composition were found between healthy and diarrheic pigs. The data visualisation using Non-Metric Multidimensional Scaling as well as by the Analysis of Similarities test suggested that the virome depended on the age of animals and differed in piglets when compared to weaned and fattening pigs.
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Smoľak et al. (2022) conducted an observational in Diarrhoea in pigs. Diarrhoea status and age vs. Healthy status and different age groups was evaluated on RNA virome composition. RNA virome composition in pigs depended on animal age, differing between piglets and older pigs, but showed no clear differences between healthy and diarrheic pigs.
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