Key result
This review summarizes current evidence regarding the treatment of patients with chronic kidney disease presenting with acute coronary syndromes, focusing on coronary revascularization strategies.
Why the study?
Do coronary revascularisation strategies improve outcomes in patients with chronic kidney disease presenting with acute coronary syndromes?
Do coronary revascularisation strategies improve outcomes in patients with chronic kidney disease presenting with acute coronary syndromes?
Despite diagnostic uncertainty and lack of direct evidence, patients with CKD and acute coronary syndromes may benefit from conventional coronary revascularisation strategies.
May support revascularization in CKD-ACS despite uncertainty; leaves open need for dedicated RCTs.
Chronic kidney disease (CKD) is associated with a high burden of coronary artery disease, myocardial infarction and cardiovascular death. Management of patients with CKD presenting with acute coronary syndromes is more complex than in the general population, due to greater diagnostic uncertainty and the lack of direct evidence for therapeutic interventions in this specific population, coupled with concerns about therapy-related adverse effects. However, these patients potentially have much to gain from conventional revascularisation strategies used in the general population. This review summarises the current evidence regarding the treatment of patients with CKD presenting with acute coronary syndromes, in particular with respect to coronary revascularisation strategies.
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Seddon et al. (2010) conducted a review in Chronic kidney disease and acute coronary syndromes. Coronary revascularisation strategies was evaluated. This review summarizes current evidence regarding the treatment of patients with chronic kidney disease presenting with acute coronary syndromes, focusing on coronary revascularization strategies.
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