Key result
In a patient-specific computational fluid dynamics simulation, decreasing the thoracic artery diameter to simulate an aneurysm almost doubled blood flow velocities during systole and generated a vonMises stress of 2.89 MPa.
Why the study?
Flow dynamics of a vessel are important to diagnose CVD in advance, but hemodynamic parameters cannot always be measured directly.
Patient-specific computational fluid dynamics simulations based on MRI can model thoracic aneurysms to assess hemodynamic parameters.
CFD may quantify thoracic aneurysm hemodynamics; leaves open clinical translation pending validation.
Nowadays cardiovascular diseases (CVDs), mostly coronary artery diseases become a leading cause of death. Flow dynamics of a vessel is important to diagnose a CVD in advance. However, hemodynamic parameters may not be measured directly. Hence, computational methods are increasingly being used in the fields of neurosurgery and cardiovascular surgery to obtain realistic physiological simulations. In this study, a patient specific thoracic artery model is first segmented based on the MRI images and then a thoracic aneurysm disease model is simulated to assess blood flow changes under the predefined conditions.
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Küçük et al. (2019) studied Thoracic aneurysm (n=1). Simulated thoracic aneurysm (vessel diameter decreased) vs. Normal vessel diameter was evaluated on Blood flow velocity and vonMises stress. In a patient-specific computational fluid dynamics simulation, decreasing the thoracic artery diameter to simulate an aneurysm almost doubled blood flow velocities during systole and generated a vonMises stress of 2.89 MPa.
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