Answers are grounded in this paper and cite their sources.
Reprogramming of mouse and human somatic cells into induced pluripotent stem (iPS) cells has been made possible with the expression of the transcription factor quartet Oct4, Sox2, c-Myc, and Klf4. Here, we compared iPS cells derived from mouse embryonic fibroblasts with the 4 factors to embryonic stem cells by electron microscopy. Both cell types are almost indistinguishable at the ultrastructural level, providing further evidence for the similarity of these 2 pluripotent stem cell populations.
No takes yet. Share an insight, caveat, or question.
Zeuschner et al. (2009) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: