Why the study?
What are the hemodynamic effects of intravenous ethacrynic acid in normal subjects compared to patients with advanced congestive heart failure?
Population
10 subjects (5 normal subjects and 5 patients with advanced congestive heart failure)
Comparison
Intravenous ethacrynic acid, 1 or 2 mg/kg vs Baseline parameters and comparison between…
Design
Other
Follow-up
90 minutes
Authors
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May improve acute hemodynamics in advanced HF; hypothesis-generating and should not yet change practice.
What are the hemodynamic effects of intravenous ethacrynic acid in normal subjects compared to patients with advanced congestive heart failure?
Intravenous ethacrynic acid improves cardiac index and reduces central venous pressure in patients with advanced congestive heart failure, contrasting with its effects in normal subjects.
A Ramirez (1968) studied this question.
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