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Traces the clinical significance of unexplained fever in heart failure and the history of body temperature assessment, highlighting thermoregulation in cardiac disease.
Very early the occurrence of fever during disease was commented upon by Hippocrates as one of its most important symptoms but not until more than 2000 years later, in the early part of the seventeenth century, were quantitative measurements of the temperature of the body obtained. Sanctorius employed
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Cohn et al. (1934) studied this question.
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