The Adrenal Glands of Mice With Hereditary Pituitary Dwarfism

Histological studies were made of the adrenal glands of mice with hereditary pituitary dwarfism. No evidence was found for a deficiency of ACTH in these mice. Quantitative comparisons with their normal sibs showed that the permanent cortex was not disproportionately small in the dwarf mice. It was confirmed that the adrenal glands of dwarf mice lack an X zone. The medulla was found to be large, relative to the permanent cortex, in both male and female dwarfs.