Key result
The qSOFA-T score demonstrated excellent discriminatory power for predicting in-hospital mortality (AUC 0.826), comparable to the GRACE score (AUC 0.840).
Why the study?
A reliable predictor is needed for non-ST-elevation myocardial infarction patients with high mortality risk.
Does the qSOFA-T score effectively predict in-hospital mortality compared to the GRACE score in patients with non-ST-elevation myocardial infarction?
Observational (n=914)
Does the qSOFA-T score effectively predict in-hospital mortality compared to the GRACE score in patients with non-ST-elevation myocardial infarction?
Answers are grounded in this paper and cite their sources.
The qSOFA-T score is a simple, easily calculated tool with excellent discriminatory power for predicting in-hospital mortality in NSTEMI patients, performing comparably to the more complex GRACE score.
OBJECTIVE: A reliable predictor is needed for non-ST-elevation myocardial infarction patients with high mortality risk. The aim of this study was to assess the effectiveness of the Global Registry of Acute Coronary Events and Quick Sequential Organ Failure Assessment-Troponin (qSOFA-T) scores on in-hospital mortality rate in non-ST-elevation myocardial infarction patients. METHODS: This is an observational and retrospective study. Patients admitted to the emergency department with acute coronary syndrome were evaluated consecutively. A total of 914 patients with non-ST-elevation myocardial infarction who met inclusion criteria were included in the study. The Global Registry of Acute Coronary Events and qSOFA scores were calculated and investigated its contribution to prognostic accuracy by adding cardiac troponin I (cTnI) concentration to the qSOFA score. The threshold value of the investigated prognostic markers was calculated by receiver operating characteristic curve analysis. RESULTS: We found the in-hospital mortality rate to be 3.4%. The area under the receiver operating characteristic curve for Global Registry of Acute Coronary Events and qSOFA-T is 0.840 and 0.826, respectively. CONCLUSION: The qSOFA-T score, which can be calculated easily, quickly, and inexpensively and obtained by adding the cTnI level, had excellent discriminatory power for predicting in-hospital mortality. Difficulty in calculating the Global Registry of Acute Coronary Events score, which requires a computer, can be considered a limitation of this method. Thus, patients with a high qSOFA-T score are at an increased risk of short-term mortality.
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Cander et al. (2023) conducted an observational in non-ST-elevation myocardial infarction (n=914). Quick Sequential Organ Failure Assessment-Troponin (qSOFA-T) score vs. Global Registry of Acute Coronary Events (GRACE) score was evaluated on in-hospital mortality (AUC 0.826). The qSOFA-T score demonstrated excellent discriminatory power for predicting in-hospital mortality (AUC 0.826), comparable to the GRACE score (AUC 0.840).
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