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January 1, 1984Pacing and Clinical Electrophysiology

Comparative Functional Effects of Chronic Ventricular Demand and Atrial Synchronous Ventricular Inhibited Pacing

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Why the study?

Does VDD pacing improve functional capacity compared to VVI pacing in patients with complete atrioventricular heart block?

Population

8 patients with complete atrioventricular heart block, age range 27-76 years.

Comparison

Atrial synchronous ventricular inhibited pacing… vs Ventricular inhibited pacing for a 3-month period.

Design

RCT, Randomly assigned to a three-month period of VDD or VVI pacing in a…

Follow-up

3 months per pacing mode

Authors

RYRaymond YeeElectrophysiologyDBDavid G. BendittElectrophysiologyWKWilliam J. KostukInterventional Cardiology

Discussion

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Implication

VDD pacing boosts peak exertional hemodynamics versus VVI in complete AV block; extends RCT evidence on physiologic pacing without improving exercise duration.

Structured PICO

Does VDD pacing improve functional capacity compared to VVI pacing in patients with complete atrioventricular heart block?

P
Population
8 patients (4 men, 4 women) with complete atrioventricular heart block, age range 27-76 years (mean 58.9 +/- 18.4 years).
I
Intervention
Atrial synchronous ventricular inhibited (VDD) pacing for a 3-month period.
C
Comparator
Ventricular inhibited (VVI) pacing for a 3-month period.
O
Outcome
Functional capacity assessed by questionnaire, graded treadmill exercise testing, and radionuclide angiocardiography.surrogate

In patients with complete AV block, VDD pacing improves maximal cardiac work during exercise compared to VVI pacing, though subjective functional capacity and exercise duration may not significantly differ.

Cite This Study

Yee et al. (1984) studied this question.

synapsesocial.com/papers/6a831ac79080d9133c4cd918https://doi.org/10.1111/j.1540-8159.1984.tb04854.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Deleterious Effects of Cardiac Pacing in a Patient with Mitral Insufficiency1977 · 21 citations
  2. 2Hemodynamic effects of altering the timing of atrial systole1963 · 178 citations
  3. 3Studies on Starling's Law of the Heart1961 · 466 citations
  4. 4Relation Between Left Ventricular Diastolic Pressure and Myocardial Segment Length and Observations on the Contribution of Atrial Systole1960 · 131 citations
  5. 5A comparison of the acute and long-term hemodynamic effects of ventricular inhibited and atrial synchronous ventricular inhibited pacing.1982 · 296 citations