Why the study?
Does a bionic baroreflex system improve systemic arterial pressure response to sudden sympathetic withdrawal in a rat model of central baroreflex failure?
Population
16 anesthetized rats (rat model of central baroreflex failure)
Comparison
Bionic baroreflex system consisting of a… vs Without the BBS
Design
Preclinical
Authors
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BBS attenuates SAP falls in rat baroreflex failure; leaves open translation to human central baroreflex restoration.
Does a bionic baroreflex system improve systemic arterial pressure response to sudden sympathetic withdrawal in a rat model of central baroreflex failure?
A bionic baroreflex system can effectively suppress systemic arterial pressure falls in a rat model of central baroreflex failure, mimicking the native baroreflex.
Sato et al. (1999) studied this question.
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