Population
Immortalized yolk sac cells, proximal tubule cell brush-border membrane vesicles extracted from mice, and…
Design
Preclinical
Authors
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Megalin/cubilin identified as ANG II receptors in vitro; hypothesis-generating for proximal tubule handling, requires in vivo validation before any clinical consideration.
Megalin acts as a receptor for angiotensin II, suggesting a novel pathway for ANG II internalization and regulation in tissues such as the proximal tubule.
González-Villalobos et al. (2004) studied this question.
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