Key result
Recent molecular tools and genetic approaches offer opportunities to overcome the limitations of conventional aggregation- and secretion-based tests for diagnosing inherited platelet function disorders.
Population
Patients with inherited platelet function disorders (IPFD)
Comparison
Molecular and genetic diagnostic tools vs Conventional aggregation- and secretion-based…
Design
Review
Authors
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Molecular diagnostics may aid inherited platelet disorder diagnosis when functional tests are inconclusive; leaves open prospective validation before routine use.
Molecular and genetic tools offer a paradigm shift in diagnosing inherited platelet function disorders, overcoming the limitations of traditional functional assays.
Nava et al. (2017) conducted a review in Inherited platelet function disorders (IPFD). Molecular investigation and genetic approaches vs. Conventional aggregation- and secretion-based tests was evaluated. Recent molecular tools and genetic approaches offer opportunities to overcome the limitations of conventional aggregation- and secretion-based tests for diagnosing inherited platelet function disorders.
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