Advances in Assessment and Treatment of ADHD Using Network Analyses

The purpose of this review is to discuss how new advances in neuroimaging and functional network analyses are applied to electroencephalography (EEG) biofeedback or neurofeedback. Clinical efficacy of one or a few scalp EEG recordings used in the treatment of attention-deficit hyperactivity disorder (ADHD) has been repeatedly demonstrated over the past 34 years. However, a problem is that improved clinical outcome often requires 40 to 80 sessions, which is expensive and difficult for patient compliance. This review cites the scientific literature of direct measures of the nodes and connections between nodes in the attention and default mode networks that are correlated with ADHD using functional magnetic resonance imaging, positron emission tomography, and EEG inverse solutions such as low-resolution electromagnetic tomography. Three-dimensional EEG biofeedback that targets dysregulation in Brodmann areas of the attention and default networks provides increased specificity and can result in improved clinical outcome in fewer sessions.