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A general protocol to prepare self-reporting photonic polymer films for specific enantiomer recognition is described. The combined molecular imprinting and colloidal crystal approach produces films with interconnected macroporous arrays and cavities that are complementary to the analyte. Binding of the analyte can be directly detected by the change in optical diffraction of the periodic macroporous array (see picture; PB=phosphate buffer).
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Hu et al. (2006) studied this question.
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