In vivo molecular imaging of breast cancer metabolic heterogeneity using [1- ¹³ C]pyruvate-d ₃ hyperpolarized by reversible exchange with parahydrogen

Stefan Petersen; Luca Nagel; Philipp Groß; Henri de Maissin; Robert Willing; Lisa Heß; Julia Mitschke; Nicole Klemm; Judith Treiber; Christoph Müller; Stephan Knecht; Ilai Schwartz; Moritz Weigt; Michael Bock; Dominik von Elverfeldt; Maxim Zaitsev; Eduard Y. Chekmenev; Jan‐Bernd Hövener; André F. Martins; Franz Schilling; Thomas Reinheckel; Andreas B. Schmidt

doi:10.7150/thno.103272

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Abstract

Our results underscore the potential of SABRE to enhance the accessibility and throughput of HP MRI, thereby advancing cancer research and diagnostic oncology.

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Petersen et al. (2025) studied this question.

synapsesocial.com/papers/6a832d1ef568d6f39593d113 https://doi.org/10.7150/thno.103272

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In vivo molecular imaging of breast cancer metabolic heterogeneity using [1- ¹³ C]pyruvate-d ₃ hyperpolarized by reversible exchange with parahydrogen

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Abstract

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In vivo molecular imaging of breast cancer metabolic heterogeneity using [1- ¹³ C]pyruvate-d ₃ hyperpolarized by reversible exchange with parahydrogen

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Abstract

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