Why the study?
Recent studies revealed the tumor-promoting effect of CTRP6 in gastrointestinal tumors, but there was no systematic discussion on its tumor-promoting mechanism.
CTRP6 promotes the development of digestive system tumors by regulating inflammation, glycolipid metabolism, and angiogenesis, suggesting it may serve as a potential diagnostic marker and therapeutic target.
CTRP6 may serve as a biomarker and target in digestive cancers; leaves open validation in prospective human studies.
Tumors of the digestive system have always received attention, and their occurrence and development are regulated by various mechanisms such as inflammation and immunity, glucose and lipid metabolism, and tumor angiogenesis. Complement Clq/TNF-related protein 6 (CTRP6) is a member of the CTRP family. It is widely expressed in various tissues and cells and plays a biological role in many aspects such as glucose and lipid metabolism and inflammation. Function. Recent studies have revealed the tumor-promoting effect of CTRP6 in gastric cancer, liver cancer, colorectal cancer and other gastrointestinal tumors, but there is no systematic discussion on the tumor-promoting mechanism of CTRP6. This article will review the role of CTRP6 in tumors of the digestive system and its possible mechanisms.
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Zhang et al. (2022) studied this question.
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