Comparison between Kimura’s disease and angiolymphoid hyperplasia with eosinophilia: case reports and literature review

Figures

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  Figure 1.. Clinical features of case 1, a 48-year-old Chinese female that presented with a progressive mass on her right mandible that was accompanied by oedema erythema and wheals mainly on the lower limbs: (a) a palpable mass that was nontender and non-erythematous, was observed in the right submandibular region; (b) wheals were scattered on her lower limbs; (c) enhanced computed tomography imaging of her nasopharynx showed a soft tissue mass (1.9 cm × 1.1 cm) in the lateral part of the right submandibular gland.

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  Figure 2.. Histopathological features of case 1, a 48-year-old Chinese female that presented with a progressive mass on her right mandible that was accompanied by oedema erythema and wheals mainly on the lower limbs: (a) preserved lymph-node architectures with hyperplastic lymphoid follicles and patchy expansion of germinal centres (haematoxylin and eosin, original magnification × 5); (b) the interfollicular region contained numerous eosinophils and interstitial fibrosis (haematoxylin and eosin, original magnification × 10); (c) eosinophilic abscesses were observed in some areas (haematoxylin and eosin, original magnification × 40). The colour version of this figure is available at: http://imr.sagepub.com.

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  Figure 3.. Clinical features of case 2, a 23-year-old Chinese female that presented with multiple nodules on the scalp without pain and itching: (a) there were numerous skin coloured nodules on the occipital area; (b) some of the nodules were approximately the size of a cherry.

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  Figure 4.. Histopathological features of case 2, a 23-year-old Chinese female that presented with multiple nodules on the scalp without pain and itching: (a) many irregular hyperplastic vessels with hypertrophic endothelium in the dermis. Endothelial cells were protruding into the lumen assuming a spiked appearance (haematoxylin and eosin, original magnification × 100); (b) the vessels were surrounded by a density of lymphocytes and a small number of eosinophils (haematoxylin and eosin, original magnification × 400). The colour version of this figure is available at: http://imr.sagepub.com.