Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study of the Effects of Tebipenem Pivoxil Hydrobromide on QT/QTc Intervals in Healthy Subjects

Figures

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  FIG 1. Mean plasma TBP concentrations following administration of single 600- or 1,200-mg oral doses (PK population).

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  FIG 2. Mean ± SD QTcF versus time by treatment (cardiodynamic population).

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  FIG 3. Mean ± SD dQTcF versus time by treatment (cardiodynamic population).

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  FIG 4. ddHR versus time-matched plasma TBP concentration (C-QT population).

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  FIG 5. ddQTcF versus time-matched plasma TBP concentration (C-QT population).

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  FIG 6. ddQTcF versus plasma TBP concentration (C-QT population).