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January 1, 2014Anaesthesia Pain & Intensive CareOpen Access

Low dose of isobaric bupivacaine provides lower incidence of spinal hypotension for hip surgery in elderly patients

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Why the study?

Does 7.5 mg of isobaric bupivacaine reduce the incidence of spinal hypotension compared to 15 mg in patients older than 60 years undergoing surgery for hip fracture?

Population

50 patients older than 60 years undergoing surgery for hip fracture

Comparison

7.5 mg of 0.5% isobaric bupivacaine as a single… vs 15 mg of 0.5% isobaric bupivacaine as a single…

Design

RCT, randomly divided into two groups

Follow-up

perioperative period (PACU stay)

Authors

LILuiz Eduardo ImbelloniSociedade Brasileira de AnestesiologiaRBRafaela Lopes BragaHospital IPOGMGeraldo Borges de Morais

Discussion

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Implication

Favors lower-dose spinal regimens to prevent hypotension in elderly hip fracture patients; extends RCT evidence for dose optimization in geriatric anesthesia.

Structured PICO

Does 7.5 mg of isobaric bupivacaine reduce the incidence of spinal hypotension compared to 15 mg in patients older than 60 years undergoing surgery for hip fracture?

P
Population
50 patients older than 60 years undergoing surgery for hip fracture
I
Intervention
7.5 mg of 0.5% isobaric bupivacaine as a single injection for spinal anesthesia
C
Comparator
15 mg of 0.5% isobaric bupivacaine as a single injection for spinal anesthesia
O
Outcome
Incidence of hypotension (defined as SBP decrease > 30% of the pressure in nursing)safety

A low dose of 7.5 mg isobaric bupivacaine for spinal anesthesia in elderly patients undergoing hip surgery provides adequate analgesia while eliminating the incidence of hypotension.

Cite This Study

Imbelloni et al. (2014) studied this question.

synapsesocial.com/papers/6a8333ded1e5557f1151b78dhttps://doi.org/10.35975/apic.v0i0.548
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Low‐dose bupivacaine with sufentanil prevents hypotension after spinal anesthesia for hip repair in elderly patients2004 · 98 citations
  2. 2Prevention of Spinal Anesthesia-Induced Hypotension in the Elderly1997 · 70 citations
  3. 3Incidence and Risk Factors for Side Effects of Spinal Anesthesia1992 · 637 citations
  4. 4A regression model for identifying patients at high risk of hypotension, bradycardia and nausea during spinal anesthesia1992 · 103 citations
  5. 5Perioperative Fluid Management and Clinical Outcomes in Adults2005 · 403 citations