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A patient is presented with a new clinical syndrome of bilateral testicular tumors and a hGH-secreting pituitary tumor associated with intermittent and extreme elevations in serum and urine cortisol. Plasma ACTH was repeatedly undetectable during the hypercortisolemia, despite the fact that urinary free cortisol levels dropped to undetectable limits after transsphenoidal hypophysectomy.
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Rosenzweig et al. (1982) studied this question.
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