Role of preoperative computed tomography in the diagnosis of acute appendicitis and reduction of negative appendectomy rates: Retrospective cross-sectional study

Background: Negative appendectomy rate (NAR) is defined as the incidence of pathologically normal appendices removed from patients suspected of having appendicitis. The objective of the present study is to determine the accuracy of CT and other modalities in diagnosing acute appendicitis, aiming to lower NAR in Saudi Arabia. Method: Retrospective analytical study conducted across 4 hospitals in Makkah and Jeddah. A net total of 913 patients got included in the study. The data were entered and coded in excel sheet, then transformed to STATA R. software for analysis. Results: A total of 911 patients who underwent appendectomy were included in this study; positive appendectomies were proven in (96.49%) of cases resulting in overall (3.51%) of cases of negative appendectomy when analyzing data based on age groups; adult patients who proceeded to the surgery based on clinical examination only had a NAR of (13.16% vs 2.66% who had one or more imagining studies P = 0.000). Conclusion: Despite the fact that the diagnosis of acute appendicitis is often challenging, the patients who proceeded to the surgery based on clinical examination only had a NAR higher than those who underwent one or more imaging studies. The NAR was higher in women than men adult patients while no relation was observed in pediatric patients. Based on the present study's findings, efficient pre-operative radiological utilization is recommended in cases presented with suspicious acute appendicitis. Moreover, investing in radiological equipment and time for proper assessment can avoid the unnecessary appendectomy.