Why the study?
Does a history of preeclampsia increase the prevalence of subclinical coronary artery disease assessed by CCTA in asymptomatic women aged 45 to 55 years compared to a population-based reference cohort?
Does a history of preeclampsia increase the prevalence of subclinical coronary artery disease assessed by CCTA in asymptomatic women aged 45 to 55 years compared to a population-based reference cohort?
May support earlier CAD screening after preeclampsia; leaves open prospective validation before practice change.
Preeclampsia is associated with an increased risk of coronary artery disease (CAD), although evidence on premature CAD development after preeclampsia is limited.1 A cross-sectional study among 491 postmenopausal women with a mean age of 67 years showed an increased prevalence of coronary artery calcification (CAC) in participants with self-reported high blood pressure during any previous pregnancy in comparison with women without such a history.2 However, the association between hypertensive pregnancy, CAC, and coronary plaque formation has not been reconfirmed in prospective studies, and there are no data on the timeline by which atherosclerosis develops in women with previous preeclampsia. The aim of this study is to compare the prevalence of coronary artery atherosclerosis of asymptomatic women aged 45 to 55 years who have a history of preeclampsia with a population-based reference cohort.
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Zoet et al. (2018) studied this question.
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