What question did this study set out to answer?

To evaluate the association between wait times for transcatheter aortic valve replacement (TAVR) and 30-day postprocedural mortality and hospital readmission.

January 5, 2019Journal of the American Heart AssociationOpen Access

Association Between Wait Time for Transcatheter Aortic Valve Replacement and Early Postprocedural Outcomes

View Full Paper

Ask AI

Bookmark

Why the study?

Increasing TAVR wait times are linked to adverse outcomes while on the wait-list, but whether prolonged wait times influence postprocedural outcomes was unknown.

Does wait time for TAVR affect 30-day all-cause mortality and readmission in patients undergoing TAVR?

Population

2170 TAVR procedures (1741 elective, 429 urgent) in Ontario, Canada

Comparison

Different wait times between initial referral and procedure

Design

Population-based study

Follow-up

30 days

Authors

GEGabby Elbaz‐GreenerInterventional Cardiology BYBrianne YarrantonSunnybrook Health Science Centre FQFeng QiuTwitter (United States)

Discussion

Member takes

Implication

Urgency status, not wait time, drives post-TAVR outcomes; leaves open whether expediting elective cases improves results.

Key Points

To evaluate the association between wait times for transcatheter aortic valve replacement (TAVR) and 30-day postprocedural mortality and hospital readmission.
Population-based study in Ontario, Canada, evaluating N=2,170 TAVR procedures (1,741 elective, 429 urgent) conducted between April 1, 2010, and March 31, 2016.
Wait time was measured from initial referral to procedure date, with nonlinear associations analyzed via multivariable regression using cubic splines.
Unadjusted and clinically adjusted models showed a significant nonlinear relationship, where shorter wait times were associated with increased hazards for 30-day mortality and readmission.
Adjustment for case urgency eliminated the association between wait time and 30-day postprocedural outcomes.
Sensitivity analyses restricted to either elective-only or urgent-only cohorts confirmed no relationship between wait times and early postprocedural outcomes.

Structured PICO

Does wait time for TAVR affect 30-day all-cause mortality and readmission in patients undergoing TAVR?

Population

2170 patients undergoing transcatheter aortic valve replacement (TAVR) procedures (1741 elective, 429 urgent) in Ontario, Canada between April 1, 2010, and March 31, 2016

Intervention

Wait time (number of days between initial referral and the procedure)

Outcome

30-day all-cause mortality and all-cause readmissionhard clinical

The apparent association between shorter TAVR wait times and worse 30-day postprocedural outcomes is entirely mediated by case urgency status.

Cite This Study

Elbaz‐Greener et al. (2019) studied this question.

synapsesocial.com/papers/6a8341d34d62b7826c1323cd https://doi.org/10.1161/jaha.118.010407

Topics

Transcatheter aortic valve replacement TAVR in low-risk patients

View Full Paper

Ask AI

Bookmark

Association Between Wait Time for Transcatheter Aortic Valve Replacement and Early Postprocedural Outcomes

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Association Between Wait Time for Transcatheter Aortic Valve Replacement and Early Postprocedural Outcomes

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider