Why the study?
Antipsychotic use can cause numerous side effects that may potentially impair rehabilitation outcomes.
Does antipsychotic use reduce functional improvement in post-acute hip fractured patients?
Does antipsychotic use reduce functional improvement in post-acute hip fractured patients?
Antipsychotic use in post-acute hip fracture patients is associated with poorer functional rehabilitation outcomes and longer rehabilitation time.
Antipsychotic use was associated with poorer functional recovery after hip fracture; leaves open causality and requires prospective trials before changing practice.
Antipsychotic (AP) use may lead to numerous side effects which may affect rehabilitation outcomes. A retrospective cohort study was carried out on 448 hip fractured patients admitted to a post-acute geriatric rehabilitation center. Functional improvement was measured by the Functional Independence Measure (FIM), motor FIM (mFIM), and mFIM effectiveness. A multiple linear regression model and regression analysis was used to evaluate the level of association between AP use and achievement of favorable functional gain. AP users exhibited lower functional ability on admission and at discharge, achieved a significantly lower functional gain and required longer rehabilitation time compared with nonusers. AP use by post-acute hip fractured patients negatively affects their chances of achieving favorable rehabilitation outcome after adjustment for confounders.
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Hershkovitz et al. (2020) studied this question.
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