Why the study?
Does subarachnoid hemorrhage increase plasma and CSF atrial natriuretic factor levels compared to unruptured cerebral aneurysms?
Population
21 patients, including 12 with nontraumatic subarachnoid hemorrhage and 9 control patients with unruptured…
Comparison
Nontraumatic subarachnoid hemorrhage (SAH) vs Unruptured cerebral aneurysms (control group)
Design
Case-control
Authors
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ANF elevation is associated with SAH severity; hypothesis-generating for fluid-electrolyte effects, prospective studies needed.
Does subarachnoid hemorrhage increase plasma and CSF atrial natriuretic factor levels compared to unruptured cerebral aneurysms?
Plasma and CSF ANF levels are significantly elevated following moderate to severe subarachnoid hemorrhage, with the extent of elevation related to hemorrhage severity rather than hemodynamic parameters.
Rosenfeld et al. (1989) studied this question.
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