Control of Renin Secretion in the Anesthetized Dog : 1) Relationship between Renin Secretion and Plasma Sodium Concentration in the Peritoneal Dialyzed Dog

The present study was made on the influence of acute change in plasma sodium level on the renin secretion in the anesthetized dog. Plasma sodium concentration was reduced by a peritoneal dialysis with low sodium lavage solution, and was returned by administration of hypertonic saline solution. The renin secretion markedly increased following a reduction of the plasma sodium level, and decreased following administration of hypertonic saline solution.