What question did this study set out to answer?

To elucidate the molecular mechanism by which plants decode calcium influx to activate CBP60g and initiate immune responses against fungal pathogens.

July 21, 2022The Plant CellOpen Access

TOUCH 3 and CALMODULIN 1/4/6 cooperate with calcium-dependent protein kinases to trigger calcium-dependent activation of CAM-BINDING PROTEIN 60-LIKE G and regulate fungal resistance in plants

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Authors

LSLifan Sun JQJun QinMinistry of Agriculture and Rural Affairs XWXiaoyun WuNanchang University

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Implication

Molecular study reveals how calcium sensors activate CBP60g to defend against fungi in Arabidopsis, highlighting a cooperative signaling network in plant immunity.

Key Points

To elucidate the molecular mechanism by which plants decode calcium influx to activate CBP60g and initiate immune responses against fungal pathogens.
Assayed pathogen-associated molecular pattern (PAMP)-triggered phosphorylation of CBP60g in Arabidopsis thaliana.
Tested direct phosphorylation and transcriptional activation of CBP60g mediated by CPK5.
Analyzed biochemical interactions among TCH3, CAM1/4/6, CPKs, and CBP60g, and evaluated resistance to soil-borne fungal pathogens.
CPK5 directly phosphorylated CBP60g upon PAMP stimulation, enhancing its transcription factor activity.
TCH3 and CAM1/4/6 interacted with the auto-inhibitory domain of CPK5, relieving auto-inhibition to promote CBP60g phosphorylation.
CPK-mediated activation of CBP60g significantly enhanced plant resistance against soil-borne fungal pathogens.

Cite This Study

Sun et al. (2022) studied this question.

synapsesocial.com/papers/6a8348c4a48d549f5e4872cd https://doi.org/10.1093/plcell/koac209

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Molecular study reveals how calcium sensors activate CBP60g to defend against fungi in Arabidopsis, highlighting a cooperative signaling network in plant immunity.

TOUCH 3 and CALMODULIN 1/4/6 cooperate with calcium-dependent protein kinases to trigger calcium-dependent activation of CAM-BINDING PROTEIN 60-LIKE G and regulate fungal resistance in plants

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Implication

Key Points

Cite This Study

TOUCH 3 and CALMODULIN 1/4/6 cooperate with calcium-dependent protein kinases to trigger calcium-dependent activation of CAM-BINDING PROTEIN 60-LIKE G and regulate fungal resistance in plants

Discussion

Member takes

Implication

Key Points

Cite This Study

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