Why the study?
Does the addition of buprenorphine to bupivacaine prolong the duration of analgesia in patients undergoing elective upper limb surgeries with brachial plexus block?
Does the addition of buprenorphine to bupivacaine prolong the duration of analgesia in patients undergoing elective upper limb surgeries with brachial plexus block?
The addition of buprenorphine to bupivacaine for brachial plexus block significantly prolongs the duration of postoperative analgesia without increasing side effects.
Supports adding buprenorphine to bupivacaine for brachial plexus block; extends RCT evidence on opioid adjuvants for prolonged regional analgesia.
Opioids are well studied adjuncts, although the evidence regarding the analgesic benefit of opioid adjuncts remains equivocal. The effectiveness of 0.5% Bupivacaine and 0.5% Bupivacaine plus buprenorphine into brachial plexus sheath was evaluated. The study was a prospective, randomized, double blind and comparative study carried out; 60 ASA I and II patients undergoing elective upper limb surgeries, aged between 16-70 years were randomly allocated into two groups of 30 each. All patients received 0.5% of Bupivacaine at 2mg/kg body weight. In addition, 30 patients in group B received Buprenorphine hydrochloride (2g/kg). Using VAS score the analgesia was evaluated every hourly for six hours, every two hours for next twelve hours and then every sixth hourly till 48 hours.
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Rajendra et al. (2015) studied this question.
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