November 1, 1994Anesthesia & Analgesia

Induction and Recovery Characteristics and Hemodynamic Responses to Sevoflurane and Halothane in Children

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Why the study?

Does sevoflurane improve recovery times and hemodynamic stability compared to halothane in children undergoing ambulatory surgery?

Population

34 children (aged 9 mo-9 yr) scheduled for ambulatory surgery

Comparison

Sevoflurane in a mixture of O2 and N2O for mask… vs Halothane in a mixture of O2 and N2O for mask…

Design

RCT, allocated randomly

Follow-up

until emergence from anesthesia

Authors

MDMarie‐Claude DuboisU.S. National Science Foundation SJStanislas JohanetU.S. National Science Foundation IMI. MuratUniversité Paris-Sud

Discussion

Member takes

Implication

Favors sevoflurane for expedited recovery in pediatric ambulatory surgery; confirms faster emergence versus halothane in RCT.

Structured PICO

Does sevoflurane improve recovery times and hemodynamic stability compared to halothane in children undergoing ambulatory surgery?

Population

34 children (aged 9 mo-9 yr) scheduled for ambulatory surgery

Intervention

Sevoflurane in a mixture of O2 and N2O (40:60) for mask induction (inspired concentrations increased every five breaths: 2%, 4%, 6%, 7%) and maintenance (1 MAC corrected for age) of anesthesia, with epidural analgesia (1% lidocaine and 0.25% bupivacaine)

Comparator

Halothane in a mixture of O2 and N2O (40:60) for mask induction (inspired concentrations increased every five breaths: 1%, 2%, 3%, 3.5%) and maintenance (1 MAC corrected for age) of anesthesia, with epidural analgesia (1% lidocaine and 0.25% bupivacaine)

Outcome

Induction and recovery characteristics, and hemodynamic profile (heart rate and systolic arterial pressure) during induction and maintenance of anesthesia

Sevoflurane provides faster recovery and better maintenance of systolic arterial pressure compared to halothane for pediatric ambulatory anesthesia.

Cite This Study

Dubois et al. (1994) studied this question.

synapsesocial.com/papers/6a836452954bb9d4ab71d4d5 https://doi.org/10.1213/00000539-199411000-00004

View Full Paper

Ask AI

Bookmark

Induction and Recovery Characteristics and Hemodynamic Responses to Sevoflurane and Halothane in Children

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Induction and Recovery Characteristics and Hemodynamic Responses to Sevoflurane and Halothane in Children

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider