The Plasma Level of N-terminal Pro B-type Natriuretic Peptide(NT-proBNP) for Severity of Coronary Artery Stenosis and Early Risk Stratification in Patients with Non ST Elevation Acute Coronary Syndrome

Ki Seok Kim; Hae Sook Han; Kyung‐Kuk Hwang; Tae Jin Youn; Dong Woon Kim; Myeong‐Chan Cho

doi:10.4070/kcj.2004.34.2.133

January 1, 2004Sunhwan'giOpen Access

The Plasma Level of N-terminal Pro B-type Natriuretic Peptide(NT-proBNP) for Severity of Coronary Artery Stenosis and Early Risk Stratification in Patients with Non ST Elevation Acute Coronary Syndrome

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Structured PICO

P

Population

50 patients with non-ST elevation acute coronary syndrome (NSTE-ACS) who presented with acute chest pain and underwent coronary angiography. Exclusions: valvular heart disease, LVEF ≤45%, renal failure, and other systemic diseases (thyroid dysfunction, liver cirrhosis, subarachnoid hemorrhage).

I

Intervention

Percutaneous coronary intervention (PCI) (n=37)

C

Comparator

Medical treatment (n=13)

O

Outcome

Relation between plasma NT-proBNP level and treatment method (PCI vs. medical treatment) and severity of coronary artery stenosissurrogate

Limitations

Blood sampling was performed at the time of coronary angiography (mean 1.9 days after admission) rather than at the emergency room, which may not accurately reflect acute phase levels
Lack of correlation analysis with echocardiographic wall motion score index
Retrospective design

Implication

Elevated plasma NT-proBNP concentrations correlate with coronary artery stenosis severity and can help predict the need for percutaneous coronary intervention in patients with non-ST elevation acute coronary syndrome.

Abstract

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Discussion

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Cite This Study

Kim et al. (2004) studied this question.

synapsesocial.com/papers/6a8364e2954bb9d4ab71d50f https://doi.org/10.4070/kcj.2004.34.2.133

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The Plasma Level of N-terminal Pro B-type Natriuretic Peptide(NT-proBNP) for Severity of Coronary Artery Stenosis and Early Risk Stratification in Patients with Non ST Elevation Acute Coronary Syndrome

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

The Plasma Level of N-terminal Pro B-type Natriuretic Peptide(NT-proBNP) for Severity of Coronary Artery Stenosis and Early Risk Stratification in Patients with Non ST Elevation Acute Coronary Syndrome

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

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