The Impact of Multimorbidity and Coronary Disease Comorbidity on Physical Function in Women Aged 80 Years and Older: The Women’s Health Initiative

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Why the study?

Does multimorbidity and coronary disease comorbidity reduce physical function in women aged 80 years and older?

Structured PICO

Does multimorbidity and coronary disease comorbidity reduce physical function in women aged 80 years and older?

Population

33,386 women aged 80 years and older enrolled in the Women's Health Initiative (WHI) from 40 U.S. clinical centers.

Intervention

Multimorbidity (presence of 2, 3, or ≥4 chronic conditions from a list of 12) and comorbidity with coronary heart disease (CHD).

Comparator

Women with 0-1 chronic condition, or women with CHD only.

Outcome

Physical functioning measured using a subscale of the RAND 36-Item Health Survey.patient reported

Multimorbidity and coronary disease comorbidity profoundly reduce physical functioning in women aged 80 years and older.

No takes yet. Share an insight, caveat, or question.

Multimorbidity linked to dose-dependent function loss in women ≥80; hypothesis-generating and should not yet change practice.

Rillamas‐Sun et al. (2016) studied this question.

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