Microfluidic paper-based analytical devices (μPADs) as enablers for the Sustainable Development Goals

The achievement of the United Nations 2030 Agenda is constrained by a global data gap, as centralized laboratories cannot deliver the dense spatiotemporal monitoring required to track Sustainable Development Goals (SDGs). This review examines Microfluidic Paper-based Analytical Devices ( μ PADs) as a decentralized, regulatory-grade sensing platform for resource-limited settings. We evaluate their contribution to six goals: Zero Hunger (SDG 2), Clean Water and Sanitation (SDG 6), Sustainable Cities (SDG 11), Responsible Consumption (SDG 12), Climate Action (SDG 13), and Life on Land (SDG 15). Beyond operational benefits, μ PADs align with Green Analytical Chemistry through biodegradable substrates and minimal reagent use. Emphasis is placed on convergence of analytical innovation and policy impact, highlighting advances including AI-assisted quantification, solid-state gas sensing, and enclosed molecular assays that enhance sensitivity and robustness. We conclude by outlining requirements for deployment, including standardization, interlaboratory validation, and digital integration to convert distributed measurements into actionable governance data.