Population
First trimester (n=6) and term (n=7) human placentas, and isolated placental villous fragments
Comparison
Incubation with GW 1929, estradiol, insulin… vs First trimester vs term placentas…
Design
Preclinical
Follow-up
up to 24 hours (incubation)
Authors
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May inform mechanisms of fetal lipid supply; leaves open human validation before any clinical relevance.
Placental LPL activity increases with gestation and is regulated by hormones such as insulin, cortisol, IGF-1, and estradiol, potentially enhancing fetal free fatty acid transport.
Magnusson-Olsson et al. (2006) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: