Ultrahigh resolution optical coherence tomography of birdshot retinochoroidopathy

Birdshot retinochoroidopathy is a rare inflammatory eye disease with typical clinical presentation and strong association with the HLA-A29 allele. Characteristic appearances on fluorescein angiogram (FA), indocyanine green (ICG) angiography, and electroretinogram (ERG) have been described.1 However, histopathology of the disease has been rare.2,3 The following case is an example of birdshot retinochoroidopathy imaged with ultrahigh resolution optical coherence tomography (UHR-OCT), capable of 3 µm axial resolution.4 UHR-OCT is able to clearly delineate individual intraretinal layers (fig 1). Figure 1  Ultrahigh resolution optical coherence tomography image from a normal eye. The intraretinal layers are labelled: NFL, nerve fibre layer, GCL, ganglion cell layer, IPL, inner plexiform layer, INL, inner nuclear layer, OPL, outer plexiform layer, ONL, outer nuclear layer, IS/OS, photoreceptor inner/outer segment junction, RPE, retinal pigment epithelium. A 64 year old man presented to the New England Eye Center (NEEC) for progressive visual deterioration despite …