In a small case series of adrenal cortical carcinoma, multimodal treatment including surgery and transcatheter arterial embolization for metastases yielded a 5-year overall survival of 62.5%.
Supports embolization in multimodal adrenal cortical carcinoma care; hypothesis-generating from Level 5 data and requires prospective validation.
INTRODUCTION: We retrospectively analyzed 6 cases of adrenal cortical carcinoma (ACC) treated during a 12-year period at a single institution. PATIENTS AND METHODS: We reviewed the clinical and pathological records and updated the follow-up of the patients treated and observed in our institution between 1995 and 2006. RESULTS: All 6 patients underwent surgery for ACC. The mean age at diagnosis was 53.3 years (range 36-72). The median follow-up was 50.7 months (range 13-132). Three patients were clinically classified as stage II, 2 as stage III and 1 as stage IV with bone metastasis. The 5-year overall survival was 62.5%. Recurrences or metastases occurred in 4 patients. Two patients without reoperation for metastases died, and others with radical treatments such as surgery, chemotherapy, transcatheter arterial embolization and/or radiation remain alive. CONCLUSIONS: In our experience, transcatheter arterial embolization was effective against liver metastasis.
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Soga et al. (2009) studied this question.
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