January 1, 2008Clinical Journal of the American Society of Nephrology
Slowing Nephropathy Progression
Why the study?
Do angiotensin-converting enzyme inhibitors and angiotensin receptor blockers reduce the decline of kidney function and proteinuria in patients with nephropathy?
Population
Patients with nephropathy or at risk of renal disease progression
Design
Review
Authors
Discussion
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Member takes
Implication
Supports ACEI/ARB preference in proteinuric nephropathy for renoprotection beyond BP lowering; leaves open optimal integration with newer agents.
Structured PICO
Do angiotensin-converting enzyme inhibitors and angiotensin receptor blockers reduce the decline of kidney function and proteinuria in patients with nephropathy?
P
Population
Patients with nephropathy or at risk of renal disease progression
I
Intervention
Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers
O
Outcome
Decline of kidney function and proteinuriasurrogate
ACE inhibitors and ARBs provide renoprotective effects and reduce proteinuria beyond their blood pressure-lowering capabilities.
Cite This Study
George L. Bakris (2008) studied this question.