October 1, 1972CancerOpen Access

Treatment of metastatic Ewing's sarcoma with BCNU

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Why the study?

Does BCNU improve tumor shrinkage in patients with metastatic Ewing's sarcoma?

Population

12 patients with metastatic Ewing's sarcoma, ranging in age from 4 to 26 years

Design

Case_series

Authors

JPJaime PalmaInstituto Tecnológico Autónomo de México SGSalman GailaniRoswell Park Comprehensive Cancer Center AFArnold I. FreemanWest Virginia University

Discussion

Member takes

Implication

Responses in this case series are hypothesis-generating; controlled trials needed before considering BCNU in metastatic Ewing's sarcoma.

Structured PICO

Does BCNU improve tumor shrinkage in patients with metastatic Ewing's sarcoma?

Population

12 patients with metastatic Ewing's sarcoma, ranging in age from 4 to 26 years

Intervention

1-3-bis chloroethyl nitrosourea (BCNU)

Outcome

Objective tumor shrinkagesurrogate

BCNU demonstrated objective tumor shrinkage in a subset of patients with metastatic Ewing's sarcoma, suggesting potential value as adjuvant chemotherapy.

Cite This Study

Palma et al. (1972) studied this question.

synapsesocial.com/papers/6a836dcc8df6316dcba9b60b https://doi.org/10.1002/1097-0142(197210)30:4<909::aid-cncr2820300408>3.0.co;2-y

View Full Paper

Ask AI

Bookmark

Treatment of metastatic Ewing's sarcoma with BCNU

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Treatment of metastatic Ewing's sarcoma with BCNU

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

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