June 15, 2005Current Medical Research and Opinion
Strategies to prevent type 2 diabetes
Why the study?
Do lifestyle modifications and pharmacologic agents (anti-diabetics, anti-hypertensives) prevent the development of type 2 diabetes in high-risk individuals?
Population
High-risk individuals with pre-diabetic conditions such as metabolic syndrome, hypertension, impaired…
Design
Review
Authors
Discussion
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Member takes
Implication
May support preventive strategies in high-risk patients; leaves open need for confirmatory randomized trials.
Structured PICO
Do lifestyle modifications and pharmacologic agents (anti-diabetics, anti-hypertensives) prevent the development of type 2 diabetes in high-risk individuals?
P
Population
High-risk individuals with pre-diabetic conditions such as metabolic syndrome, hypertension, impaired fasting glucose, family history of diabetes, obesity, or congestive heart failure
I
Intervention
Diet, exercise, oral anti-diabetic agents (metformin, acarbose, troglitazone), and anti-hypertensive agents (angiotensin converting enzyme inhibitors and angiotensin receptor blockers)
O
Outcome
Development or incidence of type 2 diabetes
Lifestyle modifications and certain pharmacologic therapies (anti-diabetics, ACEi/ARBs) may represent effective preventive strategies for type 2 diabetes in high-risk patients.
Cite This Study
Abuissa et al. (2005) studied this question.