Relation between cation and lipid content of cell walls of Pseudomonas aeruginosa, Proteus vulgaris and Klebsiella aerogenes and their sensitivity to polymyxin B and other antibacterial agents

Sensitivity to polymyxin correlated with amount of phospholipid in wall fractions of Pseudomonas aeruginosa, Proteus vulgaris and Klebsiella aerogenes and to a lesser extent with wall cation. The affinity of polymyxin for phospholipid from P. vulgaris and P. aeruginosa was the same.