Why the study?
Myxoma has been considered to undergo a simple and benign process, but this is not always the case.
Cardiac myxoma may present as part of a systemic disease entity such as Carney complex, emphasizing the utility of echocardiography in patients with breast cancer and cutaneous pigmentation.
May support echocardiography in breast cancer with pigmentation; hypothesis-generating for Carney complex links.
Background: Myxoma has been considered to undergo a simple and benign process but not always so. Case presentation: A female patient was admitted for evaluation of left breast nodule. Physical examination showed facial pigmentation, left breast nodule and 3/6 diastolic murmur at the mitral valve area. Preoperative echocardiography revealed a massive mobile left atrial mass attaching to the interatrial septum causing obstruction to mitral orifice. Histopathologic investigation confirmed the left atrial mass to be myxoma and left breast nodule to be cancer. Carney complex was considered and lifelong follow-up was advised. Conclusion: Cardiac myxoma may present as a part of a systematic disease entity. In patients with a combination of breast nodule and facial pigmentation, transthoracic echocardiography examination is advised to guide decision-making.
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Kong et al. (2021) studied this question.
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