Excretion of Radioactivity Following the Administration of ³⁵Sulfur‐Labeled Disulfiram in Man

This is the authors' abstract. We don't add key points for this paper.

Following ingestion, disulfiram is rapidly excreted in the urine and breath, with 90% of the dose gone in 3 days. In some subjects, the enzymes in the liver that oxidized diethyldithiocarbamate to carbon disulfide are very active, making this the principal metabolic pathway. However, if this pathway is not active, there is an increased excretion of DDC into the urine.